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news · 22 Jul 2026
In septic T cells, VDAC1 oligomers open a pore that leaks mtDNA and drives inflammation — and VBIT-12 shuts it down
A Shanghai team watched VDAC1 clump up, leak mtDNA, and trip the cGAS–STING alarm in immune cells — and calmed the whole thing down with the oligomerization blocker VBIT-12.
