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personal · 3 Jul 2026
Why a PSEN1 carrier ended up obsessed with mitochondria
The origin story of this blog — a genetic result, the amyloid-vs-energy argument in Alzheimer's, and the hunch that mitochondria are doing more of the driving than we give them credit for.
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news · 24 Jun 2026
x-tosis lands a $2.74M Michael J. Fox Foundation grant to push XTS001 — a brain-penetrant VDAC1-oligomerization blocker — toward Parkinson's
The most conflicted post on the site, flagged as such: x-tosis — the biotech I co-founded — just won a $2.74M grant from The Michael J. Fox Foundation to advance XTS001, an oral, brain-penetrant molecule that blocks VDAC1 oligomerization, into Parkinson's development.
